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This site is intended for US residents only

Starting  Dysport® for Pediatric Spasticity – Dysport® (abobotulinumtoxinA)

What to expect with Dysport® treatment

Dysport may help reduce muscle stiffness and improve your child’s ability to move the affected limb(s) with effects that last up to 16 weeks or longer in most patients. This means your child spends less time isolated by their spasticity symptoms and more time participating in the things they love.

Starting  Dysport® for Pediatric Spasticity – Dysport® (abobotulinumtoxinA)

What to expect with Dysport® treatment

Dysport may help reduce muscle stiffness and improve your child’s ability to move the affected limb(s) with effects that last up to 16 weeks or longer in most patients. This means your child spends less time isolated by their spasticity symptoms and more time participating in the things they love.

On injection day

Time

You should prepare to set aside enough time for your child’s Dysport appointment. You may spend anywhere from a few hours to the whole day in the doctor’s office. If your child is in school, he or she may miss some classes or activities for the day.

Emotions

We understand that getting an injection is no fun and can be stressful for everyone. There are many things you can do to help minimize stress and make the day run as smoothly as possible. Consider bringing items that can occupy your child and make them feel more comfortable, such as:

  • A favorite toy
  • Games
  • Puzzles

After injection day

Results

For the first few days or weeks, you may not see a difference in the stiffness of your child’s limb(s). In the studies, results were typically seen around 1 month after their treatment session. However, the time can vary for each child.

 

Common side effects

Mild side effects such as soreness around the injection site, cough, and runny nose are common after injection with Dysport. Your child may also feel tired afterward and want to rest. Keep an eye out for side effects, and call your child’s doctor immediately if they worsen or persist.

 

Additional therapy

As part of their spasticity management plan, your child’s doctor will likely suggest continuing with a physical therapy regimen.

The next Dysport treatment should not be given sooner than 3 months after lower limb treatment, and it should not be given sooner than 4 months after upper limb treatment. Your child’s doctor will assess your child’s spasticity at each treatment session and may adjust the dose and muscles injected.

Tracking progress with Dysport

It is helpful to track your child’s progress between injection sessions with a notebook or calendar. You can also track the goals you discussed with your child and their doctor and revisit them at the follow-up appointment.

At each treatment session, the doctor will assess your child’s progress. Based on how your child is responding to treatment, the doctor may adjust the amount of Dysport they give your child. They may also change the muscles they inject.

Communicating changes and progress with your child’s doctor is very important. It helps them make adjustments so that treatment is tailored to your child.

 

The most important safety information you should know about Dysport

Dysport may cause serious side effects, including problems breathing or swallowing and/or spread of toxin effects, that can be life threatening and death can happen as a complication. These problems can happen within hours, or days to weeks after an injection of Dysport.

 

Things to keep track of for your child’s doctor

How is your child responding to the injection?

Has their ability to move improved?

When did you start to see a response?

Has their ability to do everyday tasks improved?

Are they experiencing any side effects?

What are they?

How long do they last?

How long after their injection do you notice their symptoms of spasticity returning?

 

Annika was
compensated
for her
appearance.

 

Annika, a child with lower limb spasticity who receives Dysport treatment

“We are very pleased with how Annika is doing on Dysport. She moves smoother and faster…and she doesn’t have to work as hard….” 
“It gives her more all-over flexibility and it’s been great since day one” 
“[Her injection works for] about 3-4 months …”

Wendi, Annika’s mother

Plan ahead!

Remember to keep your child’s healthcare team informed about your plans as you may need time to schedule your next appointment, take time off from work or school, and/or arrange travel to and from the doctor’s office or clinic. Also make sure to keep them updated on your child’s progress.

What is DYSPORT?            
DYSPORT is a prescription medicine that is injected into muscles and used to treat:

  • increased muscle stiffness in people 2 years of age and older with spasticity
  • cervical dystonia in adults

IMPORTANT SAFETY INFORMATION

What is the most important information I should know about DYSPORT?            
DYSPORT may cause serious side effects that can be life threatening. These problems can happen within hours, or days to weeks after an injection of DYSPORT. Call your doctor or get medical help right away if you have any of these problems after treatment with DYSPORT: 

  • Problems swallowing, speaking, or breathing. These problems can happen within hours to weeks after an injection of DYSPORT due to weakening of associated muscles. Death can happen as a complication if you have severe problems with swallowing or breathing after treatment with DYSPORT. Swallowing problems may last for several weeks. People with certain pre-existing swallowing or breathing problems have the highest risk of getting these problems.
  • Spread of toxin effects. In some cases, the effect of botulinum toxin may affect areas of the body away from the injection site and cause symptoms of a serious condition called botulism including loss of strength and muscle weakness all over the body, double or blurred vision, drooping eyelids, hoarseness or change or loss of voice, trouble saying words clearly, loss of bladder control, and trouble breathing or swallowing.

These symptoms can happen within hours to weeks after you receive an injection of DYSPORT. These problems could make it unsafe for you to drive a car, operate machinery, or do other dangerous activities.

Who should not receive DYSPORT?

Do not receive DYSPORT if you: are allergic to DYSPORT or any of its ingredients, or to cow’s milk protein; had an allergic reaction to any other botulinum toxin product such as Myobloc®, Botox®, or Xeomin®; have a skin infection at the planned injection site.

What should I tell my doctor before receiving DYSPORT?

Tell your doctor about all your medical conditions, including if you:

  • have a disease that affects your muscles and nerves, such as amyotrophic lateral sclerosis (ALS or Lou Gehrig’s disease), myasthenia gravis, or Lambert-Eaton syndrome
  • have allergies to any botulinum toxin product or had any side effect from any botulinum toxin product in the past
  • have or have had problems with breathing (such as asthma or emphysema), swallowing, or bleeding
  • have diabetes
  • have or have had a slow heartbeat, or other problem with your heart rate or rhythm
  • have plans to have surgery or had surgery on your face
  • have weakness in or near your muscles being treated, drooping eyelids, experienced dry eye with previous use of botulinum toxin products, or any other change in the way your face normally looks
  • are pregnant (or plan to be) or breast-feeding (or planning to)

Tell your doctor about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal products. Using DYSPORT with certain other medicines may cause serious side effects. Do not start any new medicines until you have told your doctor that you have received DYSPORT in the past. Especially tell your doctor if you: have received any other botulinum toxin product in the last four months or any time in the past (be sure your doctor knows exactly which product you received); have recently received an antibiotic by injection; take muscle relaxants, an allergy or cold medicine, or a sleep medicine.

What are the possible side effects of DYSPORT?

  • The most common side effects in adults with upper limb spasticity include muscle weakness; in adults with lower limb spasticity include muscle weakness, pain in arms or legs, and falls
  • The most common side effects in children (2 to 17 years of age) with upper limb spasticity include upper respiratory tract infection and sore throat; in children with lower limb spasticity include stuffy or runny nose, sore throat, cough, and fever
  • The most common side effects in people with cervical dystonia include muscle weakness, muscle pain, difficulty swallowing, dry mouth, problems speaking, injection site pain or discomfort, feeling of tiredness, eye problems, and headache

Tell your doctor if you have any side effect that bothers you or that does not go away. These are not all the possible side effects of DYSPORT. For more information, ask your doctor or pharmacist. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

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