What is cervical dystonia (CD)?

CD is a condition that causes neck muscles to tighten or spasm, causing neck pain and making the head turn, pull in one direction, or shake.

Know the facts

You may experience involuntary contractions in your neck that cause it to make uncontrolled movements or stay in an abnormal position. The contractions may be continuous or occur as spasms. Also the abnormal head position may cause considerable pain.

CD is also called spasmodic torticollis
[spaz-mod-ik  tawr-ti-kol-is].

In some people, symptoms may seem to go away but often come back.

There is no known cause of CD, but there may be a genetic component. Find out if family members may have experienced similar symptoms.

Are you experiencing the signs & symptoms of

cervical dystonia?

CD causes muscle contractions that may cause your head to shake or twist in a different direction. You may also feel a lot of pain and discomfort.

Although there is no cure for CD, treatment is available to help relieve the abnormal position of your head and neck pain.

CD can take many forms. These are some of the most common:

Head tilting backward
Head tilting forward
Head turning to the side
Head tilting to the side

Don't wait to talk to your Doctor

Even though symptoms may disappear without treatment, recurrence is common. It’s important to discuss your symptoms with your doctor, whether or not you are currently experiencing them.

The most common form of CD is when the head turns to the side (rotational torticollis), but it’s possible for you to have a combination of different position types, depending on the muscles that are affected.

What causes cervical dystonia?

CD occurs when nerve signals in the brain tell the muscles in your neck to tighten or spasm. As stated earlier, it's not really known what causes CD, but some people with CD have other family members who also have the condition. Sometimes, CD may develop after a head, neck or shoulder injury.

Be sure to tell your doctor about any and all symptoms you’ve been having, including:

  • Continuous contractions or sudden spasms
  • Abnormal neck and head positioning
  • Pain and difficulty doing activities you were able to do before

Treatment with Dysport

Dysport is injected into the affected muscles to help lessen your symptoms.

Dysport is a type of medicine that is injected directly into affected muscles by a specialist. It helps to temporarily block signals from the brain that tell the affected muscles to contract or tighten, usually for months at a time.

Dysport significantly improved abnormal head position and neck pain

In 2 clinical studies, Dysport significantly improved abnormal position of the head and reduced neck pain at Week 4

  • In clinical trials, treatment lasted for 14 weeks for most patients
  • 25% of patients were not retreated for at least 18 weeks
  • Based on studies of patients with cervical dystonia, at least 12 weeks should pass between treatments with a botulinum toxin

Take action! Don't hold back:

  • It's important to be open and honest with your doctor about how you're feeling.
  • Together, you can create a treatment plan that's right for you
acd-team-upTEAMUP

Important Safety Information

What is the most important information I should know about Dysport?
Dysport may cause serious side effects, including problems breathing or swallowing and/or spread of toxin effects, that can be life threatening and death can happen as a complication. These problems can happen within hours, or days to weeks after an injection of Dysport.

  • Problems swallowing, breathing, or speaking. Treatment with Dysport can result in swallowing or breathing problems. People with pre-existing swallowing or breathing problems may be at greater risk following treatment with Dysport. Swallowing problems may last for several weeks; you may need a feeding tube to receive food or water. If swallowing problems are severe, food or liquids may go into your lungs.
  • Spread of toxin effects. The effects of botulinum toxin may affect areas of the body away from the injection site and cause symptoms of a serious condition called botulism which include: loss of strength and muscle weakness all over the body, double or blurred vision, and drooping eyelids, hoarseness or change or loss of voice, trouble saying words clearly, loss of bladder control, and trouble breathing or swallowing. The risk of these symptoms is probably greatest in children treated for spasticity. These problems could make it unsafe for you to drive a car, operate machinery, or do other dangerous activities.

Call your doctor or get medical help right away if you experience these problems after treatment with Dysport.

Do not receive a Dysport injection if: you are allergic to Dysport or any of its ingredients, or cow’s milk protein; you had an allergic reaction to any other botulinum toxin product, such as Myobloc®, Botox®, or Xeomin®; or you have a skin infection at the planned injection site.

Before you receive a Dysport injection tell your doctor:

  • About all your medical conditions, including if you have a disease that affects your muscles and nerves (such as ALS or Lou Gehrig’s disease [amyotrophic lateral sclerosis], myasthenia gravis, or Lambert-Eaton syndrome). You may be at increased risk of serious side effects, including difficulty swallowing or breathing.
  • If you have or have had any of the following: a side effect from any botulinum toxin in the past; problems with breathing such as asthma or emphysema; swallowing; bleeding; diabetes; and slow heartbeat, or problems with your heart rate or rhythm.
  • If you have plans to have surgery, had surgery on your face, have weakness of your forehead muscles (trouble raising your eyebrows), drooping eyelids, or any other change in the way your face normally looks.
  • If you are pregnant or breastfeeding or plan to become pregnant or breastfeed. It is not known if Dysport can harm your unborn baby or if it passes into breast milk.
  • About all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal products. Using Dysport with certain other medicines may cause serious side effects. Do not start any new medicines until you have told your doctor that you have received Dysport in the past.

Especially tell your doctor if you have received any other injections of botulinum toxin in the last four months or ever; Myobloc®, Botox®, or Xeomin® (exactly which ones); an antibiotic recently by injection; or if you take muscle relaxants; allergy, cold or sleep medicine.

Most Common Side effects of Dysport in:

  • adults with upper limb spasticity include: urinary tract infection, muscle weakness, musculoskeletal pain, fall, depression, stuffy or runny nose and sore throat, and dizziness.
  • adults with lower limb spasticity include: muscle weakness, pain in your arms or legs, and fall.
  • people with cervical dystonia include: muscle weakness, dry mouth, feeling of tiredness, muscle pain, problems speaking, eye problems, difficulty swallowing, injection site pain, and headache.
  • children (2 to 17 years of age) with lower limb spasticity include: upper respiratory infection, stuffy or runny nose and sore throat, flu, cough, and fever.

Tell your doctor if you have any side effect that bothers you or that does not go away. These are not all the possible side effects of Dysport. For more information, ask your doctor or pharmacist. You may report side effects to the FDA at www.fda.gov/medwatch or call 1-800-FDA-1088.

Indication

What is Dysport?
Dysport is a prescription medicine that is injected into muscles and used to treat:

  • increased muscle stiffness in adults with spasticity
  • cervical dystonia (CD) in adults
  • increased muscle stiffness in children 2 years of age and older with lower limb spasticity

It is not known whether Dysport is safe or effective in children under 2 years old for the treatment of lower limb spasticity; for treating other types of muscle spasms; or for treating cervical dystonia or upper limb spasticity in children under 18 years of age.

Please see Dysport Full Prescribing Information including Boxed Warning and Medication Guide.

Botox®, Xeomin®, and Myobloc® are registered trademarks of their respective owners.

Please visit www.ipsencares.com for full patient eligibility & terms and conditions.

Indications

Dysport® (abobotulinumtoxinA) for injection is indicated for the treatment of:

The safety and effectiveness of Dysport injected into upper limb muscles or proximal muscles of the lower limb for the treatment of spasticity in pediatric patients has not been established.

Safety and effectiveness in pediatric patients with lower limb spasticity below 2 years of age have not been evaluated.

Safety and effectiveness in pediatric patients with cervical dystonia or upper limb spasticity have not been established.

Click here for Full Prescribing Information and Medication Guide

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Please acquire Dysport® (abobotulinumtoxinA) from your wholesalers

If in a private practice or clinic, please select the applicable coverage benefit to acquire Dysport (abobotulinumtoxinA):

If Dysport (abobotulinumtoxinA) is covered under the medical benefit, choose the best option for your office:

To purchase Dysport (abobotulinumtoxinA) directly (buy and bill):

  • Requires upfront financial investment
  • Your office acquires Dysport directly from a select group of Specialty Distributors
  • Your office collects copay/coinsurance directly from the patient
  • Your office seeks reimbursement from payer(s)

To purchase from authorized specialty distributors of record, select from the distributors below:

Besse Medical

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Order online

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Order online

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Order online

If Dysport (abobotulinumtoxinA) is covered under the pharmacy benefit, IPSENCARES® can help you find a network specialty pharmacy:

Call IPSEN CARES® at 1-866-435-5677,

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To purchase from specialty pharmacy assignment of benefit (AOB):

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  • Patient pays copay/ coinsurance directly to Specialty Pharmacy
  • Specialty Pharmacy ships product directly to your office

Call IPSEN CARES® at 1-866-435-5677,

Monday-Friday, from 8:00 AM to 8:00 PM ET (5:00 AM to 5:00 PM PT).