What is upper limb spasticity (ULS)?

Upper limb spasticity in adults is caused by muscle spasms in the elbow, wrist, and finger muscles.

Sometimes your arms may move in ways you cannot control, jerking or twitching in what is called a spasm. Dysport treats muscle stiffness which may help lessen your symptoms.

Know the facts

ULS may develop right away after a stroke or injury, or if caused by a medical condition such as multiple sclerosis or cerebral palsy, it may take weeks, months, or even years to see symptoms. Over time, ULS may get worse

Spasticity affects an estimated 12 million people worldwide. In the US alone, that number includes about 400,000 people with cerebral palsy, 320,000 people with multiple sclerosis (MS), and more, due to stroke, spinal chord injury, and other conditions. So know that you are not alone.

Are you experiencing the signs & symptoms of

ULS can cause your muscles to contract or tense up. The extreme stiffness and tightness caused by ULS can be painful. ULS can affect movement and the ability to perform simple tasks.


Your condition could get worse over time, so see your doctor as soon as you start having symptoms.

What causes upper limb spasticity?

As mentioned earlier, ULS can happen because of different medical conditions or events, including:

  • A stroke
  • A serious injury to the brain or spinal cord
  • Diseases like cerebral palsy or multiple sclerosis

Normally, nerve cells carry messages from your brain to different parts of your body. But if a stroke, injury, or disease damages any nerve cells, then the muscles in your elbow, wrist, or fingers can receive the wrong signals. This causes them to tense up (contract) and feel stiff or tight.

Be sure to tell your doctor about any and all symptoms you’ve been having, including:

  • Muscle stiffness
  • Pain
  • Difficulty doing activities you were able to do before

Treatment with Dysport

Dysport is injected into the affected muscles to help lessen your symptoms.

Dysport is a type of medicine that is injected directly into affected muscles by a specialist. It helps to temporarily block signals from the brain that tell the affected muscles to contract or tighten, usually for months at a time. However, there are different types of botulinum toxins available.

In the clinical trial, Dysport was effective for the majority of patients at Week 4

Approximately 3 out of 4 patients had a response to treatment at Week 4, as measured by a reduction in stiffness in the elbow, wrist, or finger muscles.

  • For some people, improvement was seen 1 week after treatment

Everyone responds differently to treatment, so try not to be discouraged if it didn’t work the way you’d hoped. Be sure to talk to your doctor, as you may respond differently to another treatment option.

Take action! Don’t hold back:

  • It is important to be open and honest with your doctor about how you are feeling
  • Together, you can create a treatment plan that's right for you

Important Safety Information

What is the most important information I should know about Dysport?
Dysport may cause serious side effects, including problems breathing or swallowing and/or spread of toxin effects, that can be life threatening and death can happen as a complication. These problems can happen within hours, or days to weeks after an injection of Dysport.

  • Problems swallowing, breathing, or speaking. Treatment with Dysport can result in swallowing or breathing problems. People with pre-existing swallowing or breathing problems may be at greater risk following treatment with Dysport. Swallowing problems may last for several weeks; you may need a feeding tube to receive food or water. If swallowing problems are severe, food or liquids may go into your lungs.
  • Spread of toxin effects. The effects of botulinum toxin may affect areas of the body away from the injection site and cause symptoms of a serious condition called botulism which include: loss of strength and muscle weakness all over the body, double or blurred vision, and drooping eyelids, hoarseness or change or loss of voice, trouble saying words clearly, loss of bladder control, and trouble breathing or swallowing. The risk of these symptoms is probably greatest in children treated for spasticity. These problems could make it unsafe for you to drive a car, operate machinery, or do other dangerous activities.

Call your doctor or get medical help right away if you experience these problems after treatment with Dysport.

Do not receive a Dysport injection if: you are allergic to Dysport or any of its ingredients, or cow’s milk protein; you had an allergic reaction to any other botulinum toxin product, such as Myobloc®, Botox®, or Xeomin®; or you have a skin infection at the planned injection site.

Before you receive a Dysport injection tell your doctor:

  • About all your medical conditions, including if you have a disease that affects your muscles and nerves (such as ALS or Lou Gehrig’s disease [amyotrophic lateral sclerosis], myasthenia gravis, or Lambert-Eaton syndrome). You may be at increased risk of serious side effects, including difficulty swallowing or breathing.
  • If you have or have had any of the following: a side effect from any botulinum toxin in the past; problems with breathing such as asthma or emphysema; swallowing; bleeding; diabetes; and slow heartbeat, or problems with your heart rate or rhythm.
  • If you have plans to have surgery, had surgery on your face, have weakness of your forehead muscles (trouble raising your eyebrows), drooping eyelids, or any other change in the way your face normally looks.
  • If you are pregnant or breastfeeding or plan to become pregnant or breastfeed. It is not known if Dysport can harm your unborn baby or if it passes into breast milk.
  • About all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal products. Using Dysport with certain other medicines may cause serious side effects. Do not start any new medicines until you have told your doctor that you have received Dysport in the past.

Especially tell your doctor if you have received any other injections of botulinum toxin in the last four months or ever; Myobloc®, Botox®, or Xeomin® (exactly which ones); an antibiotic recently by injection; or if you take muscle relaxants; allergy, cold or sleep medicine.

Most Common Side effects of Dysport in:

  • adults with upper limb spasticity include: urinary tract infection, muscle weakness, musculoskeletal pain, fall, depression, stuffy or runny nose and sore throat, and dizziness.
  • adults with lower limb spasticity include: muscle weakness, pain in your arms or legs, and fall.
  • people with cervical dystonia include: muscle weakness, dry mouth, feeling of tiredness, muscle pain, problems speaking, eye problems, difficulty swallowing, injection site pain, and headache.
  • children (2 to 17 years of age) with lower limb spasticity include: upper respiratory infection, stuffy or runny nose and sore throat, flu, cough, and fever.

Tell your doctor if you have any side effect that bothers you or that does not go away. These are not all the possible side effects of Dysport. For more information, ask your doctor or pharmacist. You may report side effects to the FDA at www.fda.gov/medwatch or call 1-800-FDA-1088.


What is Dysport?
Dysport is a prescription medicine that is injected into muscles and used to treat:

  • increased muscle stiffness in adults with spasticity
  • cervical dystonia (CD) in adults
  • increased muscle stiffness in children 2 years of age and older with lower limb spasticity

It is not known whether Dysport is safe or effective in children under 2 years old for the treatment of lower limb spasticity; for treating other types of muscle spasms; or for treating cervical dystonia or upper limb spasticity in children under 18 years of age.

Please see Dysport Full Prescribing Information including Boxed Warning and Medication Guide.

Botox®, Xeomin®, and Myobloc® are registered trademarks of their respective owners.

Please visit www.ipsencares.com for full patient eligibility & terms and conditions.


Dysport® (abobotulinumtoxinA) for injection is indicated for the treatment of:

The safety and effectiveness of Dysport injected into upper limb muscles or proximal muscles of the lower limb for the treatment of spasticity in pediatric patients has not been established.

Safety and effectiveness in pediatric patients with lower limb spasticity below 2 years of age have not been evaluated.

Safety and effectiveness in pediatric patients with cervical dystonia or upper limb spasticity have not been established.

Click here for Full Prescribing Information and Medication Guide

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Call IPSEN CARES® at 1-866-435-5677,

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